Extravascular fluid losses in the perfused isolated rabbit heart
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چکیده
منابع مشابه
Radnoti Isolated Perfused Heart
The isolated perfused heart system, as originated by Oscar Langendorff more than a century ago, has become a predominant technique in pharmacological and physiological research. The technique allows the examination of cardiac contractile strength (inotropic effects), heart rate (chronotropic effects) and vascular effects without the complications of an intact animal model. From its simple begin...
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Heart vector location was estimated for 23 isolated, perfused rabbit hearts during paced ectopic beats. Twenty computer-processed signals, derived from the surface electrodes of a spherical electrolyte-filled tank containing the hearts, were optimally fitted with a locatable cardiac dipole every millisecond of the QRS and every 3rd msec of the ST-T interval. During the QRS, the computed heart v...
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The mechanical effects of ischemic contracture may be important in the development of irreversible cellular damage as it increases mechanical stress on sarcolemmal membranes and restricts endocardial perfusion. To assess the relative importance of these mechanical effects compared with decreased energy supply in the development of irreversible injury, the effects of inhibiting ischemic contract...
متن کاملThe initiation of ventricular tachycardia and fibrillation by procaine in the isolated-perfused rabbit heart.
An accelerating ventricular tachycardia ending in fibrillation can be initiated in isolated hearts by procaine injections after the administration of epinephrine, but not in untreated hearts. The run of tachycardia consists of a supraventricular or idioventricular impulse followed by an accelerating train of premature systoles coupled to it. Fibrillation results when the train reaches a frequen...
متن کاملThe Initiation of Ventricular Tachycardia and Fibrillation by Procaine in the Isolated- Perfused Rabbit Heart
An accelerating ventricular tachycardia ending in fibrillation can be initiated in isolated hearts by procaine injections after the administration of epinephrine, but not in untreated hearts. The run of tachycardia consists of a supraventricular or idioventricular impulse followed by an accelerating train of premature systoles coupled to it. Fibrillation results when the train reaches a frequen...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1959
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1959.sp006295